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Coacervation: What it is, techniques, and applications in nutraceuticals

In the panorama of encapsulation techniques, coacervation represents one of the most innovative and promising solutions.

Thanks to its versatility and the concrete results it guarantees in terms of stability and functionality, it finds application in various sectors, with particular relevance in the nutraceutical industry.

Sphera Encapsulation, the first Italian company entirely dedicated to research and development in encapsulation technologies, carries out studies and experiments in this field, offering sustainable and cutting-edge solutions.

Coacervation: The Heart of Encapsulation Technology

Coacervation is a liquid-liquid phase separation process that leads to the formation of microscopic droplets.

In practice, a homogeneous solution of charged molecules develops into two distinct phases through the interaction of oppositely charged molecules. A protective shell, often stabilized with cross-linkers, then forms around these droplets.

The result is microcapsules with dimensions ranging from 1 to 100 μm and a payload capacity of up to 70-80%.

These characteristics make them particularly useful in applications where protecting sensitive ingredients and releasing them in a targeted manner is essential.

Encapsulation Techniques and Advantages of Coacervation

Among the various encapsulation techniques, coacervation stands out for:

  • Cost-effectiveness: use of accessible materials and polymers.
  • Efficiency: ability to encapsulate large quantities of active ingredients.
  • Strength: Resistant microcapsules with high mechanical and chemical stability.
  • Sustainability: Possibility of using biodegradable materials, in line with modern environmental needs.

These advantages pave the way for solutions that are not only innovative but also environmentally friendly, encouraging the development of new applications.

Applications of Coacervation in Nutraceuticals

The nutraceutical sector, which combines nutrition and health benefits, is one of the most interested in experimenting with coacervation.

Functional ingredients, such as vitamins, probiotics, plant extracts, and essential fatty acids, are often unstable and susceptible to degradation.

Thanks to encapsulation via coacervation, however, it is possible to:

  • Improve their bioavailability.
  • Protect them from oxidation, light, and heat.
  • Control their release into the body.

This approach enables us to develop more effective and safe functional foods, thereby contributing to the growth of a constantly evolving market.

Sphera Encapsulation: Research, Experimentation, and Future Projects

Sphera Encapsulation works every day to expand the boundaries of scientific experimentation applied to encapsulation.

From the research phase to the development of customized solutions for industry, our goal is to transform science into concrete and sustainable opportunities.

If you are interested in developing new coacervation applications in the nutraceutical sector or other fields, please get in touch with us to explore innovative project opportunities. You can do so by filling out the form on this page.

Sustainable Innovation to Share

Coacervation is much more than a technique: it is a tool that combines science, health, and respect for the environment.

With the contributions of organizations like Sphera Encapsulation, the future of nutraceuticals will become increasingly sustainable, biodegradable, and focused on delivering concrete benefits to people.

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