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In the world of scientific research and innovation applied to the pharmaceutical, nutraceutical, and biomedical sectors, Drug Delivery represents one of the most strategic challenges.
Improving the efficacy of an active ingredient, making it more stable, more absorbable, and capable of reaching the desired target, is crucial today.
This is where nano-encapsulation comes in, one of the areas of excellence of Sphera Encapsulation, the first Italian company dedicated 100% to research and development in encapsulation technologies.
When we talk about Drug Delivery, we’re not referring to a single technology, but rather to a set of advanced strategies designed to deliver active ingredients more efficiently.
Nano-encapsulation represents one of the most innovative approaches: it involves trapping active ingredients inside sub-micron capsules, invisible to the naked eye but highly effective.
At Sphera Encapsulation, we focus on this concept: applying various chemical and physical techniques to produce nanocapsules that profoundly modify the behavior of the starting compound, improving its stability, bioavailability, and functionality.
Nanocapsules are microscopic structures designed to protect and transport sensitive active ingredients.
Their tiny size enables more effective interaction with biological systems, promoting cellular uptake and optimizing Drug Delivery.
Through nano-encapsulation, the active ingredient is not simply “contained,” but transformed into a more stable, manageable, and high-performance form.
This means overcoming common limitations such as premature degradation, poor solubility, or unwanted interactions with other molecules.
The benefits of nano-encapsulation are numerous and cross-application.
Among the main ones are:
• increased bioavailability of active ingredients;
• extended product shelf life;
• controlled and modulated release;
• protection of sensitive ingredients from light, oxygen, and moisture;
• modification of physicochemical properties to optimize production costs;
• easier handling of the bioactive component;
• masking of unpleasant aromas and flavors, such as that of fish oil;
• protection of the active ingredient from unwanted interactions with other molecules.
These advantages make nano-encapsulation an extremely versatile solution, capable of improving not only the efficacy of the final product but also its industrial sustainability.
One of the most important aspects of Drug Delivery is bioavailability, or the amount of active ingredient actually absorbed and utilized by the body.
Nanocapsules, thanks to their size and custom-designed structure, facilitate faster, more effective cellular absorption.
At Sphera Encapsulation, we develop nano-encapsulation systems designed to maximize this process, allowing the active ingredient to reach exactly where it’s needed, at the right time, and in the optimal amount.
Nano-encapsulation technologies are used in numerous highly innovative sectors, including:
• pharmaceutical and biomedical industries;
• nutraceuticals and food supplements;
• functional foods and innovative ingredients;
• advanced cosmetics and dermocosmetics;
• scientific research and industrial development.
After application, the result is always the same: a more effective, stable, and market-competitive product.

At Sphera Encapsulation, we believe that nano-encapsulation is not just a technology, but a proper scientific approach to Drug Delivery.
Our work is based on continuous research, experimentation, and the development of customized solutions for industrial partners and innovative companies.
Each project begins by listening to the client’s specific needs and translates those needs into advanced encapsulation systems designed to maximize the effectiveness of the starting active ingredient.
Whether you’re developing new products or improving the performance of existing solutions, can make a difference.
Contact us to discuss the development of future drug delivery projects and discover how Sphera Encapsulation technologies can support your innovation.
And to stay up-to-date on our research activities, nano-encapsulation applications, and Drug Delivery news, follow us on our social media channels. Innovation begins with knowledge.